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    Research Use Only (RUO). For laboratory research only. Not for human or veterinary use.

    Research Use Only (RUO):Research classification with product and batch documentation where available.
    Healthy Hair, Skin & Nails Blend 10 ml x 150.3 mg/ml - Avenor Peptides

    Lipotropics & vitamins

    Healthy Hair, Skin & Nails Blend

    Strength: 10 ml x 150.3 mg/ml

    A solution of nine components: seven forms of B-complex vitamins, choline and inositol. It contains no peptide. Below are published human studies on its components.

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    Batch documentationShips from Greece

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    This product is intended exclusively for laboratory research use. It is not intended for human consumption, diagnosis, treatment, or prevention of disease.

    Product information

    FormResearch product
    Strength10 ml x 150.3 mg/ml
    SKUAV-HHB-10ML
    Stock statusIn stock
    COA / BatchSee the documentation state below
    Packaging / shippingProtective professional shipping packaging with clear labelling.

    Documentation on request

    There is no published document for this specific SKU variant at the moment.

    Contact us about documentation

    Research overview

    A solution of nine components: seven forms of B-complex vitamins, choline and inositol. It contains no peptide. Below are published human studies on its components.

    What it is researched for

    Human studies on its components have looked at:

    • hair loss and hair density (biotin, dexpanthenol)
    • brittle nails (biotin)
    • skin in people with a history of skin cancers (niacinamide, ONTRAC trial)
    • acne (pantothenic acid)

    Areas of research — not a promise of results.

    How this category is positioned

    Most products in the catalogue are peptides. This is a blend of B vitamins and related nutrients, which the body also takes in from food.

    Documentation & COA

    Batch documentation and COA, where available, are linked to the specific product batch and SKU.

    This product is intended exclusively for laboratory research use. It is not intended for human consumption, diagnosis, treatment, or prevention of disease.

    Product profile

    9

    components

    7

    forms of B-complex vitamins

    150.3 mg/ml

    total concentration (sum)

    0

    peptides

    Research context

    What it is

    A solution with nine components, not a peptide.

    Seven are forms of B-complex vitamins; the other two are choline and inositol.

    150.3 mg/ml · 10 ml vial.

    The technical detail

    Niacinamide 50, thiamine hydrochloride 50, pantothenic acid 25, choline 10, inositol 10, niacin 5 mg/ml; biotin, folic acid and riboflavin 100 mcg/ml.

    Biotin and hair

    Among women with hair loss, 38% had low biotin in the blood.

    In 50 people with diffuse hair loss, with biotin and dexpanthenol (a related substance of B5) for 6 weeks, less hair fall during combing and higher hair density.

    The effect was still visible 8 weeks later.

    The technical detail

    Trüeb 2016, Int J Trichology (PMID 27601860) — recommends measuring blood biotin before supplementing · Samadi et al. 2022, Dermatol Ther (PMID 35791704), double-blind comparison of two preparations without placebo, in a different form and amounts from the blend; p<0.01 (hair fall), 0.04 and 0.02 (density).

    Biotin and nails

    Of the 45 evaluated, in 41 (91%) the improvement was definite, with firmer and harder nails.

    By electron microscopy, nail thickness increased by 25%.

    In a review of 18 cases, everyone showed clinical improvement.

    The technical detail

    Floersheim 1989, Z Hautkr (PMID 2648686), 71 started and 45 were evaluated · Colombo et al. 1990, J Am Acad Dermatol (PMID 2273113), no placebo · Patel et al. 2017, Skin Appendage Disord (PMID 28879195): all 18 cases had an underlying cause, and that is where the available evidence sits.

    Niacinamide and skin

    ONTRAC trial: 386 people with a history of skin cancers (not melanoma), niacinamide or placebo for 12 months.

    23% fewer new skin cancers.

    11–20% fewer actinic keratoses.

    The technical detail

    Chen et al. 2015, NEJM (PMID 26488693), double-blind, phase 3. The finding concerns this high-risk population and the treatment period; in a later trial of 158 transplant recipients the two groups had the same rate (Allen et al., NEJM 2023, PMID 36856616).

    Pantothenic acid and acne

    12-week trial in adults with mild to moderate acne.

    With a pantothenic acid-based supplement, 68% fewer facial lesions compared with placebo, according to the researchers.

    The technical detail

    Yang et al. 2014, Dermatol Ther (Heidelb) (PMID 24831048), P = 0.0197. Double-blind trial of a specific preparation; 48 participants, 41 completed.

    Good to know

    Biotin can affect certain laboratory tests, such as troponin (FDA).

    Niacinamide is the form of B3 studied in the ONTRAC trial.

    The technical detail

    FDA, Biotin Interference with Troponin Lab Tests (page updated 21/06/2022).

    How to read the composition

    Values are per ml, as declared by the supplier.

    Three components are declared in mcg: 100 mcg = 0.1 mg.

    The total concentration is the sum of the declared values.

    The technical detail

    50 + 50 + 25 + 10 + 10 + 5 + 0.1 + 0.1 + 0.1 = 150.3 mg/ml.

    Name and documentation

    “Healthy Hair, Skin & Nails Blend” is the supplier's trade name.

    The name is not a claim of any effect or use.

    This page describes the identity of each component and what published studies have shown.

    The technical detail

    Identity of each component: PubChem entries (see References). Certificate of Analysis per batch, where available.

    Laboratory use

    Used in a controlled laboratory setting as reference material for identity and content confirmation of the components and for solution stability studies. No administration protocol is supplied.

    Research Use Only. For laboratory research exclusively. Not intended for human or veterinary use, nor as a dietary supplement or cosmetic. The trade name is not a claim of any effect. No therapeutic, diagnostic, dietary or dosage claim is made.

    Structural data

    Niacinamide
    50 mg/ml · vitamin B3
    Thiamine hydrochloride
    50 mg/ml · vitamin B1
    Pantothenic acid
    25 mg/ml · vitamin B5
    Choline
    10 mg/ml · quaternary ammonium compound
    Inositol (myo-inositol)
    10 mg/ml · cyclic polyol
    Niacin
    5 mg/ml · vitamin B3
    Biotin
    100 mcg/ml · vitamin B7
    Folic acid
    100 mcg/ml · vitamin B9
    Riboflavin
    100 mcg/ml · vitamin B2
    Total concentration
    150.3 mg/ml (sum of declared values)
    Vial volume
    10 ml
    Form
    Solution in a vial (not a lyophilised powder)
    Category
    Blend of B-complex vitamins, choline and inositol — contains no peptide
    Trade name
    Healthy Hair, Skin & Nails Blend (supplier's trade name)
    Composition source
    As declared by the supplier

    Documentation

    • Composition as declared by the supplier.
    • Certificate of Analysis (CoA) per batch, where available.
    • Documentation is tied to the specific batch and its SKU.

    References

    References & documentation

    1. 1.PubChem CID 936 — Nicotinamide.
    2. 2.PubChem CID 6202 — Thiamine hydrochloride.
    3. 3.PubChem CID 6613 — Pantothenic acid.
    4. 4.PubChem CID 305 — Choline.
    5. 5.PubChem CID 892 — myo-Inositol.
    6. 6.PubChem CID 938 — Niacin.
    7. 7.PubChem CID 171548 — Biotin.
    8. 8.PubChem CID 135398658 — Folic acid.
    9. 9.PubChem CID 493570 — Riboflavin.
    10. 10.Floersheim G.L. (1989). Treatment of brittle fingernails with biotin. Z Hautkr, 64(1), 41-48. PMID 2648686.
    11. 11.Colombo V.E. et al. (1990). Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. J Am Acad Dermatol, 23(6 Pt 1), 1127-1132. PMID 2273113.
    12. 12.Patel D.P. et al. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disord, 3(3), 166-169. PMID 28879195.
    13. 13.Chen A.C. et al. (2015). A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention. N Engl J Med, 373(17), 1618-1626. PMID 26488693.
    14. 14.Allen N.C. et al. (2023). Nicotinamide for Skin-Cancer Chemoprevention in Transplant Recipients. N Engl J Med, 388(9), 804-812. PMID 36856616.
    15. 15.Yang M. et al. (2014). A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne. Dermatol Ther (Heidelb), 4(1), 93-101. PMID 24831048.
    16. 16.Almohanna H.M. et al. (2019). The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatol Ther (Heidelb), 9(1), 51-70. PMID 30547302.
    17. 17.Kamanna V.S. et al. (2009). The mechanism and mitigation of niacin-induced flushing. Int J Clin Pract, 63(9), 1369-1377. PMID 19691622.
    18. 18.FDA. Biotin Interference with Troponin Lab Tests (updated 2022).
    19. 19.Trüeb R.M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. Int J Trichology, 8(2), 73-77. PMID 27601860.
    20. 20.Samadi A. et al. (2022). Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands. Dermatol Ther, 35(9), e15695. PMID 35791704.

    Product information

    Frequently asked questions

    Is Healthy Hair, Skin & Nails Blend a peptide?
    No. It is a blend of nine components: seven forms of B-complex vitamins, choline and inositol. It contains no peptide.
    What does 150.3 mg/ml mean?
    It is the sum of the declared amounts per ml: 50 + 50 + 25 + 10 + 10 + 5 mg, plus three components at 100 mcg (0.1 mg each) = 150.3 mg/ml.
    Where does the composition come from?
    From the supplier's composition declaration. Where a Certificate of Analysis is available for the batch, it is linked to the corresponding SKU.
    Does the name describe an effect?
    No. “Healthy Hair, Skin & Nails Blend” is the trade name under which the supplier sells the blend. It is not a claim of any effect or use.
    Are there human studies?
    Yes, on individual components: biotin in brittle nails and in hair loss, niacinamide in skin (ONTRAC trial, NEJM 2015) and pantothenic acid in acne. Details are in the section “What human studies have shown”.
    What do we know about biotin and hair?
    Among women with hair loss, 38% had low biotin in the blood, and the researcher recommends measuring it first (Trüeb, 2016). In a trial of 50 people with diffuse hair loss, with biotin and dexpanthenol for 6 weeks, hair fall decreased and density increased (Samadi et al., 2022). In a review of 18 cases, everyone who took biotin for hair or nails showed clinical improvement (Patel et al., 2017).
    Does biotin affect blood tests?
    According to the FDA, it can affect certain laboratory tests, such as troponin.
    What is the difference between niacin and niacinamide?
    They are two forms of vitamin B3. Niacinamide is the form studied in the ONTRAC trial on skin.