Composition
Four ingredients, 226 mg per ml.
10 ml vial.
The technical detail
GABA 100 mg/ml; L-arginine 100 mg/ml; L-glutamine 25 mg/ml; melatonin 1 mg/ml.
Research Use Only (RUO):Research classification with product and batch documentation where available.
Lipotropics & vitamins
Relaxation Blend
Strength: 10 ml x 226 mg/ml
Relaxation Blend is a four-ingredient product in a 10 ml vial: GABA, L-arginine, L-glutamine and melatonin, with a total amount of 226 mg per ml. Three of the ingredients are amino acids and the fourth is a hormone of the pineal gland.
€75,00
In stock
1
The more products, the bigger the discount
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3 → −8%
4 → −11%
5+ → −15%
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Batch documentationShips from Greece
Free shipping: Greece from €50, Cyprus and Bulgaria from €100, France, Germany, Italy, Belgium, Netherlands, Spain, Austria, Czechia, Denmark, Estonia, Finland, Hungary, Ireland, Lithuania, Luxembourg, Latvia, Poland, Portugal, Romania, Sweden and Slovakia from €200. Details
This product is intended exclusively for laboratory research use. It is not intended for human consumption, diagnosis, treatment, or prevention of disease.
Product information
FormResearch product
Strength10 ml x 226 mg/ml
SKUAV-RP226-10ML
Stock statusIn stock
COA / BatchSee the documentation state below
Packaging / shippingProtective professional shipping packaging with clear labelling.
Documentation on request
There is no published document for this specific SKU variant at the moment.
Contact us about documentationResearch overview
Relaxation Blend is a four-ingredient product in a 10 ml vial: GABA, L-arginine, L-glutamine and melatonin, with a total amount of 226 mg per ml. Three of the ingredients are amino acids and the fourth is a hormone of the pineal gland.
Each of the four ingredients has a large literature of its own: GABA in neurotransmission, arginine in nitric oxide synthesis, glutamine in nitrogen metabolism and melatonin in the biological clock.
Documentation & COA
Batch documentation and COA, where available, are linked to the specific product batch and SKU.
This product is intended exclusively for laboratory research use. It is not intended for human consumption, diagnosis, treatment, or prevention of disease.
Product profile
4
ingredients
226 mg/ml
total amount
10 ml
vial volume
AV-RP226-10ML
SKU code
Research context
The ingredients
GABA is a neurotransmitter; arginine and glutamine are amino acids.
Melatonin is a hormone of the pineal gland.
The technical detail
GABA: GABA-A receptors (Olsen & Sieghart 2008); arginine: substrate of NOS (Morris 2006); glutamine: glutamate–glutamine cycle (Bak 2006); melatonin: MT1/MT2 receptors (Jockers 2016).
What research shows
There are human studies of each ingredient separately.
Blood and urine markers and the rhythm of melatonin secretion were measured.
The technical detail
Li 2015 (n=12); Bode-Böger 1998 (n=8); Lowe 1990 (n=7); Lewy 1980 (n=6); Burgess 2008 (n=27).
Status
No study of the four combined was found.
Supplied for laboratory research only.
The technical detail
The data concern each ingredient separately.
Laboratory use
It is intended for use in a controlled laboratory setting as a material of declared composition, according to the supplier’s documentation.
Research Use Only. Exclusively for laboratory and research use. Not intended for human or veterinary use, or for the diagnosis, treatment or prevention of any condition. It is not a medicine, a food or a dietary supplement.
Structural data
- GABA (gamma-aminobutyric acid)
- 100 mg/ml — C4H9NO2, 103.12 g/mol, CAS 56-12-2
- L-arginine
- 100 mg/ml — C6H14N4O2, 174.20 g/mol, CAS 74-79-3
- L-glutamine
- 25 mg/ml — C5H10N2O3, 146.14 g/mol, CAS 56-85-9
- Melatonin
- 1 mg/ml — C13H16N2O2, 232.28 g/mol, CAS 73-31-4
- Total
- 226 mg/ml, 10 ml vial
Documentation
- The SKU code and the amount per vial are stated on the product label.
References
References & documentation
- 1.Petroff OA (2002). Neuroscientist, 8(6), 562-73. PMID 12467378.
- 2.Olsen RW et al. (2008). Pharmacol Rev, 60(3), 243-60. PMID 18790874.
- 3.Boonstra E et al. (2015). Front Psychol, 6, 1520. PMID 26500584.
- 4.Li J et al. (2015). Front Pharmacol, 6, 260. PMID 26617516.
- 5.Morris SM Jr (2006). Am J Clin Nutr, 83(2), 508S-512S. PMID 16470022.
- 6.Bode-Böger SM et al. (1998). Br J Clin Pharmacol, 46(5), 489-97. PMID 9833603.
- 7.Walsh NP et al. (1998). Sports Med, 26(3), 177-91. PMID 9802174.
- 8.Lacey JM et al. (1990). Nutr Rev, 48(8), 297-309. PMID 2080048.
- 9.Bak LK et al. (2006). J Neurochem, 98(3), 641-53. PMID 16787421.
- 10.Lowe DK et al. (1990). Am J Clin Nutr, 52(6), 1101-6. PMID 2122714.
- 11.Claustrat B et al. (2005). Sleep Med Rev, 9(1), 11-24. PMID 15649735.
- 12.Jockers R et al. (2016). Br J Pharmacol, 173(18), 2702-25. PMID 27314810.
- 13.Lewy AJ et al. (1980). Science, 210(4475), 1267-9. PMID 7434030.
- 14.Burgess HJ et al. (2008). J Physiol, 586(2), 639-47. PMID 18006583.
- 15.PubChem. Compound summary CID 119 (GABA). National Library of Medicine.
- 16.PubChem. Compound summary CID 6322 (L-arginine). National Library of Medicine.
- 17.PubChem. Compound summary CID 5961 (L-glutamine). National Library of Medicine.
- 18.PubChem. Compound summary CID 896 (melatonin). National Library of Medicine.
Product information
Frequently asked questions
What does Relaxation Blend contain?
Per ml: GABA 100 mg, L-arginine 100 mg, L-glutamine 25 mg and melatonin 1 mg. A total of 226 mg per ml, in a 10 ml vial.
What is GABA?
It is gamma-aminobutyric acid, a neurotransmitter of the mammalian central nervous system. The nerve cell synthesises it from glutamic acid.
What is the role of L-arginine?
It is the amino acid from which the body produces nitric oxide, and it takes part in the urea cycle.
What is L-glutamine?
It is the most abundant free amino acid in human plasma and muscle. It carries nitrogen between tissues.
What is melatonin?
It is a hormone synthesised and secreted by the pineal gland. The rhythm of its secretion follows the light/dark cycle.
Are there studies of the four combined?
No published study of the four ingredients together was found. The studies mentioned here concern each ingredient separately.
Is any ingredient a peptide?
No. Three are amino acids and melatonin is an indole derivative.
Is it a medicine or a dietary supplement?
No. It is supplied exclusively as a material for laboratory research.
Can it be used by humans or animals?
No. It is intended for laboratory and research use only.
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