What it is
A synthetic tripeptide of three amino acids: Glu-Asp-Arg.
Publications refer to it as the EDR peptide.
The technical detail
Tripeptide Glu-Asp-Arg, C15H26N6O8, 418.40 g/mol, CAS 175175-23-2 (PubChem CID 10273502).
Research Use Only (RUO):Research classification with product and batch documentation where available.
Short peptides
Pinealon
Strength: 10 mg
Pinealon is a synthetic tripeptide with the sequence Glu-Asp-Arg (EDR). In the literature it is called the “EDR peptide” and is studied mainly in cultures of nerve cells.
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This product is intended exclusively for laboratory research use. It is not intended for human consumption, diagnosis, treatment, or prevention of disease.
Product information
FormResearch product
Strength10 mg
SKUAVR-PIN-10MG
Stock statusIn stock
COA / BatchSee the documentation state below
Packaging / shippingControlled shipping preparation according to the available SKU variant.
Documentation on request
There is no published document for this specific SKU variant at the moment.
Contact us about documentationResearch overview
Pinealon is a synthetic tripeptide with the sequence Glu-Asp-Arg (EDR). In the literature it is called the “EDR peptide” and is studied mainly in cultures of nerve cells.
It interests researchers as a small molecule for studying oxidative stress and the interaction of short peptides with DNA in nerve cells.
Documentation & COA
Batch documentation and COA, where available, are linked to the specific product batch and SKU.
This product is intended exclusively for laboratory research use. It is not intended for human consumption, diagnosis, treatment, or prevention of disease.
Product profile
3
amino acids — the tripeptide Glu-Asp-Arg
418.40
molecular weight (g/mol)
EDR
its name in the publications
10 mg
amount per vial
Research context
How it acts
The mechanism is a working hypothesis.
An interaction of the peptide with DNA has been described.
The technical detail
Partial entry into the major groove of DNA and interaction with N7 and O6 of guanine (Silanteva 2019).
What research shows
Studies in cultures of nerve cells.
Free radicals and oxidative DNA damage were measured.
The technical detail
Khavinson 2011 (rat cerebellar granule cells, PC12); Kraskovskaya 2024 (induced neurons from elderly donors’ fibroblasts).
Status
The data are mainly preclinical.
Supplied for laboratory research only.
The technical detail
Preclinical data.
Laboratory use
It is intended for use in a controlled laboratory setting, in in vitro studies of oxidative stress in nerve-cell cultures and in biophysical studies of peptide–DNA interaction.
Research Use Only. Exclusively for laboratory and research use. Not intended for human or veterinary use, or for the diagnosis, treatment or prevention of any condition. It is not a medicine, a food or a dietary supplement.
Structural data
- Class
- Synthetic tripeptide
- Sequence
- Glu-Asp-Arg (EDR)
- Molecular formula
- C15H26N6O8
- Molecular weight
- 418.40 g/mol
- CAS
- 175175-23-2
- PubChem CID
- 10273502
Documentation
- The SKU code and the amount per vial are stated on the product label.
References
References & documentation
- 1.Khavinson V et al. (2011). Rejuvenation Res, 14(5), 535-41. PMID 21978084.
- 2.Kraskovskaya N et al. (2024). Int J Mol Sci, 25(21). PMID 39518916.
- 3.Silanteva IA et al. (2019). J Phys Chem B, 123(9), 1896-1902. PMID 30762356.
- 4.PubChem. Compound summary CID 10273502 (Glu-Asp-Arg). National Library of Medicine.
Product information
Frequently asked questions
What is Pinealon?
It is a synthetic tripeptide with the sequence Glu-Asp-Arg. In scientific publications it is called the EDR peptide.
What does “EDR” mean?
It is the one-letter code of its three amino acids: E for glutamic acid, D for aspartic acid and R for arginine.
In which cells has it been studied?
Mainly in nerve cells in the laboratory, such as rat cerebellar granule cells and neurons generated from human fibroblasts.
Are there studies in humans?
Publications in humans are few and small. Research in humans is at an early stage and most of the data are preclinical.
Is it a medicine or a dietary supplement?
No. This product is supplied exclusively as a material for laboratory research.
Can it be used by humans or animals?
No. It is intended for laboratory and research use only.
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